ATR-IN-12

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ATR-IN-12

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

ATR-IN-12 (Compound 5g) 是一种有效的共济失调毛细血管扩张和 Rad3 相关 (ATR) 激酶抑制剂，IC₅₀值 0.007 μM。ATR-IN-12 显示出良好的抗肿瘤活性并显着降低 ATR 及其下游信号蛋白的磷酸化水平。ATR-IN-12 是一种很有前途的先导化合物，可用于后续针对 ATR 激酶的药物发现。

生物活性	ATR-IN-12 (Compound 5g) is a potent inhibitor of ataxia telangiectasia and Rad3-related (ATR) kinase with anIC₅₀value of 0.007 μM. ATR-IN-12 displays good anti-tumor activity and significantly reduces the phosphorylation level ofATRand its downstream signaling protein. ATR-IN-12 is a promising lead compound for subsequent drug discovery targetingATRkinase^[1].
分子量	441.55
Formula	C₂₂H₂₇N₅O₃S
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.