ATM Inhibitor -4 (化合物 39) 是一种强效的选择性ATM抑制剂,其IC50为 0.32 nM。ATM Inhibitor-4 对PI3K激酶家族有较强的抑制作用。ATM Inhibitor-4 在 1 μM 时能完全抑制mTOR。ATM Inhibitor-4 具有良好的代谢稳定性。
生物活性 | ATMInhibitor-4 (compound 39) is a potent and selectiveATMinhibitor, with anIC50of 0.32 nM.ATMInhibitor-4 shows stronger inhibition ofPI3Kkinases family.ATMInhibitor-4 shows a full inhibition ofmTORat 1 μM.ATMInhibitor-4 exhibits favorable metabolic stability[1]. |
IC50& Target | ATM 0.32 nM (IC50) | PI3K | mTOR |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |