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Antitumor agent-28
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Antitumor agent-28图片
CAS NO:2097499-67-5
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Antitumor agent-28 选择性调节共济失调毛细血管扩张突变 (ATM) 激酶。Antitumor agent-28 可预防 ATM 介导的疾病并具有有效的抗癌活性。
生物活性

Antitumor agent-28 selectively inhibits ataxia telangiectasia mutated (ATM) kinase. Antitumor agent-28 preventsATMmediated disease and has potent anti-cancer activity[1].

IC50& Target[1]

ATM

 

ATR

 

体外研究
(In Vitro)

Antitumor agent-28 inhibits ataxia telangiectasia mutated (ATM; IC50=7.6 nM; HT29 cells), ataxia telangiectasia and Rad3-related protein (ATR; IC50=18 μM; HT29 cells), PI3Ka (IC50=0.24 μM; BT474 cells). Antitumor agent-28 does not inhibit mTOR in MDA-MB-468 cells[1].

分子量

512.62

Formula

C25H32N6O4S

CAS 号

2097499-67-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.