CAS NO: | 2241914-86-1 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Aurora Kinases-IN-2 (compound 12Aj) is a potentAurora kinasesinhibitor withIC50values of 90 and 152 nM forAurora AandAurora B. Aurora Kinases-IN-2 arrests cell cycle at G2/M phase by regulating cyclin B1 and cdc2. Aurora Kinases-IN-2 can be used forcancerresearch[1]. | ||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | Aurora Kinases-IN-2 (compound 12Aj) (72 hours) has antiproliferative activity with IC50values of 11.5 μM, 1.34 μM, 7.30 μM and 1.64 μM for U87, HeLa, HepG2 and LoVo tumor cell lines, respectively[1]. Western Blot Analysis[1]
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分子量 | 435.86 | ||||||||
Formula | C22H18ClN5O3 | ||||||||
CAS 号 | 2241914-86-1 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |