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Aurora inhibitor 1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Aurora inhibitor 1图片
CAS NO:2227019-45-4
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Aurora inhibitor 1 是一种有效的Aurora抑制剂,抑制Aurora AAurora B激酶的IC50分别 ≤4 nM 和 ≤13 nM。
生物活性

Aurora inhibitor 1 is a potentAurorainhibitor with anIC50of ≤ 4 nM and ≤13 nM forAurora AandAurora Bkinase, respectively[1].

IC50& Target

Aurora A

4 nM (IC50)

Aurora B

13 nM (IC50)

体外研究
(In Vitro)

Aurora inhibitor 1 (Compound 16) exhibits Kdvalues of 0.01 nM for both Aurora A and Aurora B kinase[1].

体内研究
(In Vivo)

Aurora inhibitor 1 (Compound 16) exhibits good drug exposure levels across species upon oral dosing, and shows excellent in vivo efficacy in a mouse xenograft tumor model when dosed orally[1].

分子量

459.57

Formula

C23H25N9S

CAS 号

2227019-45-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.