CAS NO: | 2227019-45-4 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Aurora inhibitor 1 is a potentAurorainhibitor with anIC50of ≤ 4 nM and ≤13 nM forAurora AandAurora Bkinase, respectively[1]. | ||
IC50& Target |
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体外研究 (In Vitro) | Aurora inhibitor 1 (Compound 16) exhibits Kdvalues of 0.01 nM for both Aurora A and Aurora B kinase[1]. | ||
体内研究 (In Vivo) | Aurora inhibitor 1 (Compound 16) exhibits good drug exposure levels across species upon oral dosing, and shows excellent in vivo efficacy in a mouse xenograft tumor model when dosed orally[1]. | ||
分子量 | 459.57 | ||
Formula | C23H25N9S | ||
CAS 号 | 2227019-45-4 | ||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |