| CAS NO: | 13721-39-6 |
| 包装 | 价格(元) |
| 10mM (in 1mL Water) | 电议 |
| 5g | 电议 |
| 25g | 电议 |
| Cas No. | 13721-39-6 |
| 别名 | 钒酸钠 |
| 化学名 | trisodium;trioxido(oxo)vanadium |
| Canonical SMILES | [O-][V](=O)([O-])[O-].[Na+].[Na+].[Na+] |
| 分子式 | Na3O4V |
| 分子量 | 183.91 |
| 溶解度 | ≥ 6.7mg/mL in Water |
| 储存条件 | Store at 2-8°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue. In the presence of oxidizing agents vanadium ions exist as the hydrated monomer of Sodium orthovanadate (vanadate: HVO42- or H2VO4-) at micromolar concentations near neutral pH. Sodium orthovanadate (vanadate) also begins to polymerize at concentrations greater than 0.1 mM at neutral pH. The yellow-orange solutions of decavanadate can be converted to the colorless solutions of monomeric Sodium orthovanadate (vanadate) by dilution after a period of many hours. The process is hastened by boiling at pH 10, which encourages the kinetically sluggish depolymerization process[1]. Sodium orthovanadate could alter the phosphorylation status of ASK1 at serine 83 and threonine 845 induced by ischemia. Sodium orthovanadate could increase the tyrosine posphorylation of PTEN and further inhibit the activation of ASK1 via activating Akt during cerebral ischemia[2]. References: |
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