CAS NO: | 222036-17-1 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | GW8510 is a potentcyclin-dependent kinase-2 (CDK2)inhibitor. GW8510 is also aribonucleotide reductase M2 (RRM2)inhibitor. GW8510 exhibits neuroprotective and anticancer activities[1][2][3]. | ||||||||||||||||
IC50& Target[1][2] |
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体外研究 (In Vitro) | GW8510 (0.5-4 μM; 72 h) 以剂量依赖性方式抑制 HCT116 细胞的活力[2]。 Cell Viability Assay[2]
Western Blot Analysis[2]
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体内研究 (In Vivo) | GW8510 与 Tamoxifen 联用可通过诱导自噬增强对他莫昔芬耐药的 BBC 异种移植物的杀瘤作用[3]。 | ||||||||||||||||
分子量 | 449.51 | ||||||||||||||||
Formula | C21H15N5O3S2 | ||||||||||||||||
CAS 号 | 222036-17-1 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |