CAS NO: | 848249-10-5 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | HS-243 is a potent and selectiveIRAK-4andIRAK-1inhibitor, withIC50values of 20 and 24 nM. HS-243 shows minimalTAK1(transforming growth factor β-activated kinase 1) inhibition activity, with aIC50of 0.5 μM. HS-243 shows anti-inflammatory and anticancer activity[1]. | ||||||||||||||||
IC50& Target |
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体外研究 (In Vitro) | HS-243 (0-10 μM, 24 h) inhibits cell survival by 21% for AN3-CA (pancreatic cancer cell), and 13% for SKOV-3 (ovarian cancer cell)[1]. Cell Viability Assay[1]
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分子量 | 324.33 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C17H16N4O3 | ||||||||||||||||
CAS 号 | 848249-10-5 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 41.67 mg/mL(128.48 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |