CAS NO: | 2229974-83-6 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | XY028-140 is aPROTACconnected by ligands forCereblonandCDK. XY028-140 inhibits both CDK4/6 expression and CDK4/6 activity incancercells[1]. | ||||||||||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | A375 melanoma and T47D breast cancer cells are treated with 0.3 or 1 μΜ XY028-140 for 24 hours. XY028-140 inhibits both CDK4/6 expression and CDK4/6 activity[1]. | ||||||||||||||||
分子量 | 760.80 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C39H40N10O7 | ||||||||||||||||
CAS 号 | 2229974-83-6 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 5.56 mg/mL(7.31 mM;ultrasonic and warming and heat to 60℃) 配制储备液
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以下溶剂前显示的百
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