HDAC10-IN-1 (化合物 13b) 是一种有效的和高选择性的HDAC10抑制剂，其IC50为 58 nM。HDAC10-IN-1 可调节侵袭性 FLT3-ITD 阳性急性髓系白血病细胞的自噬。
| 生物活性 | HDAC10-IN-1 (compound 13b) is a potent and highly selectiveHDAC10inhibitor, with anIC50of 58 nM. HDAC10-IN-1 modulatesautophagyin aggressive FLT3-ITD positive acute myeloid leukemia cells[1]. |
| IC50& Target | HDAC10 58 ± 10 nM (IC50) | hHDAC8 920 ± 170 nM (IC50) | hHDAC6 2420 ± 530 nM (IC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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