| CAS NO: | 6202-27-3 |
| 包装: | 500mg |
| 市场价: | 347元 |
| Cas No. | 6202-27-3 |
| 别名 | 桑色素.桑黄素 |
| 化学名 | 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one hydrate |
| Canonical SMILES | OC1=C(C(C(O)=C2)=CC=C2O)OC3=CC(O)=CC(O)=C3C1=O.O |
| 分子式 | C15H10O7.H2O |
| 分子量 | 320.25 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Morin hydrate is a plant flavonoid extracted from yellow Brazil wood with anti-oxidant properties. Previous studies have shown that morin hydrate could protect cells against oxygen radical damage. In vitro: Morin hydrate at 75-100 μM protected against the oxidation of low density lipoprotein (LDL) induced by free radicals [1]. Morin hydrate at 100 μM concentration effectively inhibited Cu2+-induced oxidation of human LDL [2]. In cultured rat glomerular mesangial cells attacked by oxyradicals, the survival time of the cells was doubled with using morin hydrate [3]. 0.25 – 2.0 mM morin prolonged the survival of rat hepatocytes against free radical damage triggered by xanthine oxidase-hypoxanthine [4]. Morin hydrate could inhibit the amyloid formation by islet amyloid polypeptide and disaggregated amyloid fibers [5]. In vivo: In a 80 min ischemia rat model, treatment of morin at 2.5, 5.0 and 10 μmol/Kg reduced liver necrosis by 51.48 ± 9.94%, 66.55 ± 2.18%, and 79.37 ± 11.03%, respectively [3]. References: |
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