CAS NO: | 2328074-38-8 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | EML741 is a histone lysine methyltransferaseG9a/GLPinhibitor, with anIC50of 23 nM,Kdof 1.13 μM for G9a. EML741 also inhibitsDNMT1(IC50, 3.1 μM), with no effect on DNMT3a or DNMT3b. EML741 exhibits low cell toxicity, and is membrane permeable and blood-brain barrier penetrated[1]. | |||
IC50& Target[1] |
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体外研究 (In Vitro) | EML741 (Compound 12a) shows a similar high inhibition potency against G9a (97%, 98% inhibition at 10 μM and 25 μM, respectively) and GLP (95%, 98% inhibition at 10 μM and 25 μM, respectively)[1]. | |||
分子量 | 523.75 | |||
Formula | C31H49N5O2 | |||
CAS 号 | 2328074-38-8 | |||
运输条件 | Room temperature in continental US; may vary elsewhere. | |||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |