UNC2399,一种生物素化的 UNC1999,是选择性的EZH2降解剂,对 EZH2 具有很高的体外效力,IC50值为 17 nM。
生物活性 | UNC2399, a biotinylated UNC1999, is a selectiveEZH2degrader, maintaining high in vitro potency forEZH2, with anIC50of 17 nM[1][2]. |
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体外研究 (In Vitro) | UNC2399 (1-1000 nM) displays high in vitro potency (IC50=17±2 nM) in the EZH2 radioactive biochemical assay[1]. UNC2399 (100 μM) enriches EZH2 from HEK293T cell lysates[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |