JAK-IN-3 (compound 22) 是一种有效的JAK抑制剂,其对 JAK3、JAK1、TYK2 和JAK2 的IC50值分别为 3 nM、5 nM、34 nM 和 70 nM。
生物活性 | JAK-IN-3 (compound 22) is a potentJAKinhibitor, withIC50values of 3 nM, 5 nM, 34 nM and 70 nM forJAK3,JAK1,TYK2andJAK2, respectively[1]. |
IC50& Target[1] | JAK3 3 nM (IC50) | JAK1 5 nM (IC50) | Tyk2 34 nM (IC50) | JAK2 70 nM (IC50) |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |