PKC-theta inhibitor 1 是PKCθ抑制剂，Ki值为 6 nM，在体内抑制 IL-2 产生，IC50为 0.19 μM。PKC-theta inhibitor 1 减轻了多发性硬化小鼠模型中疾病症状。
| 生物活性 | PKC-theta inhibitor 1 is thePKCθinhibitor with anKivalue of 6 nM, inhibitsIL-2production in vivo with anIC50of 0.19 μM. PKC-theta inhibitor 1 demonstrates a reduction of symptoms in a mouse model of multiple sclerosis[1]. |
| IC50& Target[1] | PKCθ 6 nM (Ki) | PKCδ 392 μM (Ki) | PKCα 1020 μM (Ki) | IL-2 production 0.19 μM (IC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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