CAS NO: | 374922-43-7 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | CAY10602 is aSIRT1activator. CAY10602 dose-dependently suppresses the NF-κB-dependent induction of TNF-α by lipopolysaccharide in THP-1 cells[1]. | ||||||||||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | Compounds (including CAY10602/compound 1) with SIRT1-activating properties have a significant effect on fat mobilization in differentiated adipocytes, and these compounds (including CAY10602) have antiobesity and/or antidiabetic properties. Compounds (including CAY10602) with SIRT1 activating potential exert strong suppression of TNF-α release at concentrations between 20 and 60 μM[1]. | ||||||||||||||||
分子量 | 418.44 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C22H15FN4O2S | ||||||||||||||||
CAS 号 | 374922-43-7 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 41.67 mg/mL(99.58 mM;Need ultrasonic) 配制储备液
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以下溶剂前显示的百
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