CAS NO: | 711085-63-1 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | PNU-282987 (free base) is a potentα7 nicotinic acetylcholine receptor (nAChR)agonist with anEC50of 154 nM. PNU-282987 (free base) is also a functional antagonist of the5-HT3receptorwith anIC50of 4541 nM. PNU-282987 (free base) can be used for the research of central and peripheral nervous systems[1]. | ||||||||
IC50& Target |
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体外研究 (In Vitro) | PNU-282987 (free base) (Compound C7) displaces the R7 selective antagonist methyllycaconitine (MLA) from rat brain homogenates with a Kiof 27 nM[1]. | ||||||||
体内研究 (In Vivo) | PNU-282987 (free base) (Compound C7) (i.v.; 1, 3 mg/kg) leads to a reversal of the gating deficit[1].
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分子量 | 264.75 | ||||||||
Formula | C14H17ClN2O | ||||||||
CAS 号 | 711085-63-1 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |