| CAS NO: | 154-02-9 |
| 包装 | 价格(元) |
| 25mg | 电议 |
| 100mg | 电议 |
| Cas No. | 154-02-9 |
| 别名 | 5-羟基色醇 |
| 化学名 | 5-hydroxy-1H-indole-3-ethanol |
| Canonical SMILES | OCCC1=CNC2=C1C=C(O)C=C2 |
| 分子式 | C10H11NO2 |
| 分子量 | 177.2 |
| 溶解度 | ≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 5-hydroxy Tryptophol is a metabolite of tryptophan. Tryptophan (encoded by the codon UGG) is an α-amino acid that is used in the biosynthesis of proteins. Tryptophan has an α-amino group, an α-carboxylic acid group, and a side chain indole, demonstrating it as a non-polar, aromatic amino acid. Tryptophan is critical in humans, but the body cannot synthesize it and therefore tryptophan must be obtained from the diet. Tryptophan is also found to be a precursor to the neurotransmitters serotonin and melatonin. In vitro: In previous studies, 5-hydroxy tryptophol was identified as a metabolite of tryptophan that was formed by the alcohol dehydrogenase-catalyzed reduction of the serotonin intermediate, 5-hydroxyindoleacetaldehyde. Moreover, depending on the tissue NAD/NADH ratio, the acetaldehyde intermediate could also be oxidized by aldehyde dehydrogenase to form 5-hydroxyindoleacetic acid. Therefore, the ratio of 5-hydroxy tryptophol to 5-hydroxyindoleacetic acid could be used as a biomarker for recent alcohol consumption [1,2]. In vivo: Up to now, there is no animal in vivo data reported. Clinical trial: So far, no clinical study has been conducted. References: |
m.cnreagent.com