Sancycline (Bonomycin) 是一种罕见的半合成四环素，由 Declomycin 的氯和苄基羟基部分氢解制备。
| Cas No. | 808-26-4 |
| 别名 | 山环素; Bonomycin; 6-Demethyl-6-deoxytetracycline |
| Canonical SMILES | O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])CC4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)N |
| 分子式 | C21H22N2O7 |
| 分子量 | 414.41 |
| 溶解度 | DMSO : 10 mg/mL (24.13 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Sancycline is a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin.Target:Like other tetracyclines, sancycline acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site. |
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