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Dalfopristin(RP54476)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dalfopristin(RP54476)图片
CAS NO:112362-50-2
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
1mg电议
5mg电议
10mg电议

产品介绍
Dalfopristin (RP54476) 是一种半合成的链霉素抗生素。
Cas No.112362-50-2
别名达福普汀; RP54476
Canonical SMILESO=S(CCN(CC)CC)([C@H]1[C@@](C(O[C@H]([C@@H](/C=C/C(NC/C=C\C(C)=C\2)=O)C)C(C)C)=O)([H])N(C(C3=COC(CC(C[C@@H]2O)=O)=N3)=O)CC1)=O
分子式C34H50N4O9S
分子量690.85
溶解度DMSO : ≥ 3 mg/mL (4.34 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dalfopristin is a semi-synthetic streptogramin antibiotic. Quinupristin/Dalfopristin (Q/D) is a valuable alternative antibiotic to vancomycin for the treatment of multi-drug resistant Enterococcus faecium infections.

Quinupristin/Dalfopristin(Q/D) is a combination of streptogramins B (Quinupristin) and streptogramins A (Dalfopristin) at 30:70 ratio[1]. Quinupristin/Dalfopristin, a semisynthetic injectable streptogramin, is a combination of 2 synergistic antibiotic components that are derived from pristinamycin: a type B streptogramin (Quinupristin) and a type A streptogramin (Dalfopristin), in a 30:70 weight-to-weight ratio[2].

[1]. Wang S, et al. Characteristic of Enterococcus faecium clinical isolates with quinupristin/Dalfopristin resistance in China. BMC Microbiol. 2016 Oct 21;16(1):246. [2]. Sacar M, et al. Comparison of antimicrobial agents as therapy for experimental endocarditis: caused by methicillin-resistant Staphylococcus aureus. Tex Heart Inst J. 2010;37(4):400-4.