CAS NO: | 71675-92-8 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
生物活性 | (S)-Amisulpride (Esamisulpride) is a potentdopamine D2/D3receptorantagonist. (S)-Amisulpride is an antagonist at the5-HT7receptorwith aKIof 900 nM. (S)-Amisulpride has antipsychotic and antidepressant effects[1][2]. | ||||||||||||||||
IC50& Target[1][2] |
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体外研究 (In Vitro) | (S)-Amisulpride (Esamisulpride) displays high affinity binding at both D2and D3receptors and is approximately twice as potent as racamisulpride and 20–50 times more potent than (R)-amisulpride at these receptors[2] | ||||||||||||||||
体内研究 (In Vivo) | The (S)-amisulpride (10mg/kg, s.c.) stimulus is rapidly acquired and was shown to be dose-related, time dependent (effective between 30 and 120min) and stereoselective male C57BL/6 mice[1]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 369.48 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C17H27N3O4S | ||||||||||||||||
CAS 号 | 71675-92-8 | ||||||||||||||||
中文名称 | (S)-氨磺必利 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 100 mg/mL(270.65 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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