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Sarpogrelate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sarpogrelate图片
CAS NO:125926-17-2
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
沙格雷酯
MCI-9042 free acid
产品介绍
Sarpogrelate (MCI-9042) 是一种新的特异性5-HT2受体拮抗剂,具有口服活性,Sarpogrelate 可以增加血小板聚集,有止血作用,可被用于伯格氏病的研究。
生物活性

Sarpogrelate (MCI-9042) is a new, specific orally active5-HT2receptor antagonist, Sarpogrelate increases platelet aggregation and has hemostasis effect, and can be used for the research of Buerger’s disease[1].

IC50& Target

5-HT2Receptor

 

体外研究
(In Vitro)

Sarpogrelate (MCI-9042) induces a significant decrease in plasma serotonin (5-HT) concentration and after 2 weeks increases significantly the concentration of whole blood 5-HT[1].
Sarpogrelate increases significantly plasma tryptophan concentration after 2 and 4 weeks, and no changes in plasma 5-HIAA concentration[1].
Sarpogrelate also has a tendency to increase the concentration of whole blood tryptophan concentration, did not show significant changes in platelet aggregation induced by ADP and collagen[1].
Sarpogrelate increases significantly platelet aggregation induced by serotonin after 2 weeks[1].

Clinical Trial
分子量

429.51

Formula

C24H31NO6

CAS 号

125926-17-2

中文名称

沙格雷酯

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.