DSP-1053 是一种苄基哌啶衍生物，一种有效的血清素转运蛋白 (SERT) 抑制剂，Ki值为 1.02 nM。DSP-1053 显示5-HT1A受体部分激动活性，Ki值为 5.05 nM。DSP-1053 具有抗抑郁活性。
| 生物活性 | DSP-1053, a benzylpiperidine derivative, is a potent serotonin transporter(SERT)inhibitor with aKiof 1.02 nM. DSP-1053 shows partial 5-HT1Areceptor agonistic activity with aKiof 5.05 nM. DSP-1053 has antidepressant activity[1]. |
| IC50& Target[1] | 5-HT1AReceptor 5.05 nM (Ki) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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