CAS NO: | 113294-82-9 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Angiopeptin, a cyclic octapeptide analogue of somatostatin, is a weaksst2/sst5receptor partial agonist withIC50values of 0.26 nM and 6.92 nM, respectively. Angiopeptin is a potent inhibitor of growth hormone release andinsulin-like growth factor-1 (IGF-1)production. Angiopeptin inhibitsadenylate cyclaseor stimulates extracellular acidification. Angiopeptin has the potential for coronary atherosclerosis research[1][2]. |
IC50& Target | IC50: 0.26 nM (sst2) and 6.92 nM (sst5)[1][2] |
体外研究 (In Vitro) | Angiopeptin (0.1 nM- 10 μM; for 1 h) acts as a partial agonist (pEC50=6.57) with a maximum response of 423% at 3 μM on the release of tritium on CHO hsst2cells[2]. |
体内研究 (In Vivo) | Angiopeptin (20 and 50μg/kg; i.h.) significantly inhibits neointimal formation[1]. |
分子量 | 1098.34 |
Formula | C54H71N11O10S2 |
CAS 号 | 113294-82-9 |
Sequence Shortening | {Nal}CYWKVCT-NH2 |
中文名称 | 血管抑肽 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |