GHK是由甘氨酸、L-组氨酸和L-赖氨酸残基依次连接组成的三肽。
| Cas No. | 49557-75-7 |
| 别名 | 甘氨酰-L-组氨酰-L-赖氨酸 |
| Canonical SMILES | O=C(N[C@H](C(O)=O)CCCCN)[C@@H](NC(CN)=O)CC1=CN=CN1 |
| 分子式 | C14H24N6O4 |
| 分子量 | 340.4 |
| 溶解度 | DMSO: 2.5mg/mL,PBS (pH 7.2): 10mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | GHK is a peptide released during extracellular matrix (ECM) protein degradation following tissue injury. It binds to copper to form GHK-Cu, a complex with diverse biological activities, including roles in tissue remodeling and wound healing, hair growth, and suppression of inflammation. GHK (1 µM) increases keratinocyte proliferation in vitro, as well as the number of cells positive for the keratinocyte stem cell marker p63 and the protein levels of integrin α6 and β1 in a skin equivalent model. It also reduces infiltration of inflammatory cells and decreases TNF-α and IL-6 protein levels in bronchoalveolar lavage fluid (BALF) in a mouse model of pulmonary fibrosis induced by bleomycin . |
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