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FR900098(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
FR900098(sodium salt)图片
CAS NO:73226-73-0
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Cas No.73226-73-0
别名FR900098味精盐
Canonical SMILESCC(N(O)CCCP([O-])(O)=O)=O.[Na+]
分子式C5H11NO5P•Na
分子量219.1
溶解度DMF: Inso,DMSO: Inso,Ethanol: Inso,PBS (pH 7.2): 5mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

FR900098 is a derivative of fosmidomycin that has antimalarial activity (IC50s = 170, 170, and 90 nM for HB3, A2, and Dd2 P. falciparum strains, respectively). FR900098 inhibits DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis, in vitro in a dose-dependent manner. FR900098 (>10 mg/kg, i.p.) eradicated P. vinckei parasites within four days in mice.