Pregnenolone monosulfate sodium-13C2,d2 is the 13C- and deuterium labeled Pregnenolone monosulfate sodium. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium salt acts as a signaling-specific inhibitor ofcannabinoidCB1receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by theCB1receptors. Pregnenolone monosulfate sodium salt can protect the brain from cannabis intoxication^[1][2]. Pregnenolone monosulfate sodium salt is also aTRPM3 channelactivator, and also can weakly activateTRPM1 channels^[3].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

422.52

C₁₉¹³C₂H₂₉D₂NaO₅S

2483824-22-0

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.