包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | CCR1 antagonist11 hydrochloride (A1B1) is an orally activeCCR1antagonist with theIC50values of 0.03 μM, 0.58 μM and 0.32 μM for hCCR1, mCCR1 and rCCR1, respectively.CCR1 antagonist11 hydrochloride can be used in the study of rheumatoid arthritis and other related inflammatory diseases[1]. | ||||||||||
IC50& Target | IC50: 0.03 μM (hCCR1),0.58 μM (mCCR1), 0.32 μM (rCCR1)[1]. | ||||||||||
体外研究 (In Vitro) | CCR1 antagonist 11 hydrochloride(A1B1) inhibits MIP-1α-induced Ca2+mobilization in THP-1 cells with the IC50value of 1 nM[1]. | ||||||||||
体内研究 (In Vivo) | The pharmacokinetic parameters of CCR1 antagonist 11 hydrochloride(A1B1) in rat
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分子量 | 466.38 | ||||||||||
Formula | C23H26Cl2FN3O2 | ||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |