CAS NO: | 158535-55-8 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | a-Helical Corticotropin Releasing Factor (12-41) is a 30amino acidslong, α-helical analogue of corticotropin releasing factor/hormone. Corticotropin releasing factor (CRF) is a hypothalamic hormone, which stimulates the secretion of adrenocorticotrophic hormone (ACTH). a-Helical Corticotropin Releasing Factor (12-41) would suppress the stimulatory effect[1][2]. | ||||||||
体外研究 (In Vitro) | a-Helical Corticotropin Releasing Factor (0.3 nM; 5-min pulses every 40 min alternately) shows the inhibitory effect on stimulated release of immunoreactive ACTH from perifused equine anterior pituitary cells in vitro.[2]. | ||||||||
体内研究 (In Vivo) | a-Helical Corticotropin Releasing Factor (12-41) (15-150 μg; s.c.; isolated for 30 or 60 min) suppresses the active behavioral response characteristic of guinea pig pups to brief isolation in novel surroundings[1].
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分子量 | 3497.01 | ||||||||
Formula | C152H251N43O47S2 | ||||||||
CAS 号 | 158535-55-8 | ||||||||
Sequence Shortening | FHLLREMLEMAKAEQEAEQAALNRLLLEEA-NH2 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |