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CXCR4 modulator-2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CXCR4 modulator-2图片
CAS NO:2488943-55-9
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
CXCR4 modulator-2 (compound Z7R) 是一种高效的CXCR4调节剂,IC50为 1.25 nM。CXCR4 modulator-2 在小鼠血清中具有可接受的稳定性 (t1/2= 77.1 min),在小鼠水肿模型中表现出抗炎活性。
生物活性

CXCR4modulator-2 (compound Z7R) is a highly potentCXCR4modulator with anIC50value of 1.25 nM.CXCR4modulator-2 has acceptable stability (t1/2= 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model[1].

IC50& Target[1]

CXCR4

1.25 nM (IC50)

体内研究
(In Vivo)

CXCR4 modulator-2 (10 mg/kg; IP; single dosage) significantly reduces the edema weights (~50%) in the lesion and decreases the expression of CXCR4s[1].

Animal Model:male nude mice (6 weeks, 20 g; subcutaneous injection of 50 μL of λ-carrageenan)[1]
Dosage:10 mg/kg
Administration:IP; single dosage
Result:Significantly reduced the edema weights (~50%) in the lesion and decreased the expression of CXCR4s.
分子量

428.53

Formula

C21H32N8O2

CAS 号

2488943-55-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.