CAS NO: | 92-43-3 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
500mg | 电议 |
1 g | 电议 |
5 g | 电议 |
生物活性 | Phenidone, an orally active dual inhibitor ofcyclooxygenase (COX)andlipoxygenase(LOX), ameliorates rat paralysis in experimental autoimmune encephalomyelitis. Phenidone is a potent hypotensive agent in the spontaneously hypertensive rat[1][2]. Phenidone is used as a photographic developer[3]. | ||||||||||||||||
IC50& Target[1] |
| ||||||||||||||||
体外研究 (In Vitro) | Phenidone significantly inhibits the increases in COX-1/-2 and 5-LOX in the spinal cords of rats with experimental autoimmune encephalomyelitis (EAE)[1]. | ||||||||||||||||
体内研究 (In Vivo) | Phenidone inhibits the formation of vascular lipoxygenase products and to reduce blood pressure in the AII-dependent renovascular hypertensive rat[2]. | ||||||||||||||||
分子量 | 162.19 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C9H10N2O | ||||||||||||||||
CAS 号 | 92-43-3 | ||||||||||||||||
中文名称 | 菲尼酮 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 100 mg/mL(616.56 mM;Need ultrasonic) H2O : 3.33 mg/mL(20.53 mM;ultrasonic and warming and heat to 60℃) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |