您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > N-Benzoyl-(2R,3S)-3-phenylisoserine
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
N-Benzoyl-(2R,3S)-3-phenylisoserine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-Benzoyl-(2R,3S)-3-phenylisoserine图片
CAS NO:132201-33-3
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议

产品介绍
N-Benzoyl-(2R,3S)-3-phenylisoserine是紫杉醇C-13的侧链,对紫杉醇较强的抗肿瘤活性至关重要。
Cas No.132201-33-3
别名N-苯甲酰基-(2R,3S)-3-苯基异丝氨酸
Canonical SMILESO=C(C1=CC=CC=C1)N[C@](C2=CC=CC=C2)([H])[C@@H](O)C(O)=O
分子式C16H15NO4
分子量285.29
溶解度DMSO : ≥ 160 mg/mL (560.83 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N-Benzoyl-(2R,3S)-3-phenylisoserine is a Taxol C-13 Side Chain and crucial for the strong antitumor activity of Taxol[1].

[1]. Iwao Ojima, et al. Efficient and Practical Asymmetric Synthesis of the Taxol C-13 Side Chain, N-Benzoyl-(2R,3S)-3-phenylisoserinea,n d Its Analogues via Chiral3-Hydroxy-4-aryl-&lactams through Chiral Ester Enolate-Imine Cyclocondensation.