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N-Desmethyl Galanthamine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-Desmethyl Galanthamine图片
CAS NO:41303-74-6
包装:1mg
市场价:900元

产品介绍
N-DesmethylGalanthamine是的Galanthamine的代谢物。Galanthamine是一种有效的乙酰胆碱酯酶(AChE)抑制剂,IC50为500nM。
Cas No.41303-74-6
别名N-去甲加兰他敏(加兰他敏杂质E),N-Norgalanthamine
Canonical SMILESO[C@H]1C=C[C@@]23CCNCC4=CC=C(OC)C(O[C@@]3([H])C1)=C24
分子式C16H19NO3
分子量273.33
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N-Desmethyl Galanthamine is a metabolite of Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM[1][2].

[1]. Bachus R, et al. The O-demethylation of the antidementia drug galanthamine is catalysed by cytochrome P450 2D6. Pharmacogenetics. 1999;9(6):661-668. [2]. Melanie-Jayne R. Howes, et al. Acetylcholinesterase inhibitors of natural origin. International Journal of Research in Pharmaceutical and Biomedical Sciences 3(SI 1):67-86.