CAS NO: | 1196509-60-0 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | AZD7594 is a potent selective nonsteroidalglucocorticoid receptormodulator, with anIC50of 0.9 nM. | ||||||||||||||||
IC50& Target | IC50: 0.9 nM (Glucocorticoid receptor)[1] | ||||||||||||||||
体外研究 (In Vitro) | AZD7594 is a potent selective nonsteroidal glucocorticoid receptor modulator, with an IC50of 0.9 nM. AZD7594 shows no effect on progesterone receptor, mineralocorticoid receptor, Androgen receptor, ERα or ERβ (IC50, >10 μM). | ||||||||||||||||
体内研究 (In Vivo) | AZD7594 has anti-inflammatory activity, and efficiently inhibits rat lung edema[1]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 606.62 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C32H32F2N4O6 | ||||||||||||||||
CAS 号 | 1196509-60-0 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
| ||||||||||||||||
溶解性数据 | In Vitro: DMSO : ≥ 83.3 mg/mL(137.32 mM) *"≥" means soluble, but saturation unknown. 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |