包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | EGFR-IN-62 (compound 9h) is a potent and reversibleEGFRkinase inhibitor, withIC50values of 10 nM (L858R/T790 M), 29 nM (WT), and 242 nM (L858R/T790 M/C797S), respectively. EGFR-IN-62 shows antiproliferative activity against A549 and H1975 cell lines, withIC50values of 2.53 and 1.56 μM, respectively. EGFR-IN-62 induces dose-dependentapoptosisprocess, G1/G0-phase arrestation, and the inhibition of motility on A549 and/or H1975 cell lines[1]. | |||
IC50& Target |
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分子量 | 551.64 | |||
Formula | C30H33N9O2 | |||
运输条件 | Room temperature in continental US; may vary elsewhere. | |||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |