EGFR-IN-22 是一种有效的EGFR抑制剂,对野生型EGFR和EGFRL858R/T790M/C797S的IC50分别为 4.91 nM 和 0.54 nM (CN112538072A,化合物 243)。
生物活性 | EGFR-IN-22 is a potentEGFRinhibitor withIC50s of 4.91 nM and 0.54 nM forwild typeEGFRandEGFRL858R/T790M/C797S, respectively (CN112538072A, compound 243)[1]. |
IC50& Target[1] | EGFRL858R/T790M/C797S 0.54 nM (IC50) | EGFR (WT) 4.91 nM (IC50) |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |