Antitumor agent-73

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Antitumor agent-73

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

Antitumor agent-73 是 Diosgenin (HY-N0177) 的衍生物，能够抑制STAT3信号通路，外源激活Pdia3/ERp57。Antitumor agent-73 对多种癌细胞具有强抗肿瘤活性，且是 Diosgenin 的 7.9 -341.7 倍。

生物活性

Antitumor agent-73 is aDiosgenin(HY-N0177) derivative, which inhibitsSTAT3signaling and activatesPdia3/ERp57exogenously. Antitumor agent-73 shows potent anti-tumor activity against variouscancercell lines, 7.9-341.7-fold stronger than Diosgenin^[1].

IC₅₀& Target

STAT3

体外研究
(In Vitro)

Antitumor agent-73 (compound 2.2f) shows anti-proliferative activity against cancer cells with IC₅₀s of 0.1847 μM (Aspc-1), 4.038 μM (H358), 4.001 μM (HCT116), 0.4483 μM (SW620), respectively^[1].

分子量

858.06

Formula

C₅₀H₈₂BrO₄P

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.