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JTP10-△-TATi TFA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
JTP10-△-TATi TFA 是选择性的JNK2多肽抑制剂,其IC50值为 92 nM,对 JNK2 的选择性是JNK1 和 JNK3 的10倍以上。
生物活性

JTP10-△-TATi TFA is a selectiveJNK2peptide inhibitor, with anIC50of 92 nM, exhibiting 10-fold selectivity forJNK2overJNK1andJNK3[1].

IC50& Target[1]

JNK2

92 nM (IC50)

JNK1

1.16 μM (IC50)

JNK3

1.2 μM (IC50)

体外研究
(In Vitro)

JTP10-△-TATi TFA inhibits the migration of PyVMTjnk2+/+cells and PyVMTjnk2-/-cells expressing GFP-JNK2α[1].

分子量

2833.28

Formula

C120H213F3N48O28

Sequence Shortening

Ac-PKRPTTLNLF-{Ahx}-RRRQRRKKRG-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

 ContentsAssign value
Acidic amino acidAsp (D), Glu (E), and the C-terminal -COOH.-1
Basic amino acidArg (R), Lys (K), His (H), and the N-terminal -NH2+1
Neutral amino acidGly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)0

3.  Recommended solution:

Overall charge of peptideDetails
Negative (<0)1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0)1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.