p38 MAP Kinase Inhibitor IV is a highly specific ATP-competitivep38αMAPKinhibitor withIC₅₀s of 0.13 and 0.55 μM forp38αandp38βMAPK, respectively^[1].

p38 MAP Kinase Inhibitor IV (MT4) shows IC₅₀values of 0.13, 0.55, 5.47, and 8.63μM for p38α, β, χ, andδ, respectively. p38 MAP Kinase Inhibitor IV has the suppressive action on the release of TNF-alpha and IL-1beta in PBMC with IC50 values of 22 and 44 nM, respectively^[1].

456.94

C₁₂H₄Cl₆O₄S

1638-41-1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.