(Z)-GW 5074 是一种化合物,可以与突变型亨廷顿蛋白 (mHTT) 和LC3相互作用,但对野生型 HTT 无作用。(Z)-GW 5074 可抑制c-Raf的活性,不影响自噬,在神经退行性疾病中有效。
生物活性 | (Z)-GW 5074 is a compound which interacts with bothmHTT (mutanthuntingtinprotein)andLC3, but not but not with the wild-type HTT protein. (Z)-GW 5074 inhibitsc-Raf, shows no effect onautophagy, and is effective for neurodegenerative disorder[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |