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Ezatiostat
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ezatiostat图片
CAS NO:168682-53-9
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议

产品介绍
理化性质和储存条件

Name: Ezatiostat
CAS#: 168682-53-9 (free base)
Chemical Formula: C27H35N3O6S
Exact Mass: 529.22466
Molecular Weight: 529.6483
Elemental Analysis: C, 61.23; H, 6.66; N, 7.93; O, 18.12; S, 6.05
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Technical InformationSynonym: TLK199; TLK-199; TLK 199; Ezatiostat; TER-199; TLK-199 hydrochloride; TER 199; TLK 199 hydrochloride; TER199; TLK199 hydrochloride; trade name: Telintra
Chemical Name: (S)-ethyl 2-amino-5-(((R)-3-(benzylthio)-1-(((S)-2-ethoxy-2-oxo-1-phenylethyl)amino)-1-oxopropan-2-yl)amino)-5-oxopentanoate
InChi Key: GWEJFLVSOGNLSS-FIXSFTCYSA-N
InChi Code: InChI=1S/C27H35N3O6S/c1-3-35-26(33)21(28)15-16-23(31)29-22(18-37-17-19-11-7-5-8-12-19)25(32)30-24(27(34)36-4-2)20-13-9-6-10-14-20/h5-14,21-22,24H,3-4,15-18,28H2,1-2H3,(H,29,31)(H,30,32)/t21-,22-,24-/m0/s1
SMILES Code: O=C(OCC)[C@@H](N)CCC(N[C@@H](CSCC1=CC=CC=C1)C(N[C@@H](C2=CC=CC=C2)C(OCC)=O)=O)=O
实验参考方法


Patients who responded to ezatiostat under-expressed miR-129 (A) and over-expressed miR-155 (B). J Hematol Oncol. 2012 May 6;5:20.


Three pathways, mTOR, JAK2, and JNK, were under-expressed in patients who responded to ezatiostat. J Hematol Oncol. 2012 May 6;5:20.