包装: | 500 μg |
市场价: | 7200元 |
生物活性 | Cyclic ADP-ribose ammonium (cADPR ammonium) is a potent second messenger forcalcium mobilizationthat is synthesized from NAD+by an ADP-ribosyl cyclase. Cyclic ADP-ribose ammonium increases cytosolic calcium mainly byRyanodine receptor-mediated release from endoplasmic reticulum and also by extracellular influx through the opening ofTRPM2 channels[1][2][3]. |
IC50& Target | Calcium mobilization[1] |
体外研究 (In Vitro) | cADPR (20 nM) elicits a large rapid Ca2+release in sea urchin eggs homogenates[1]. |
体内研究 (In Vivo) | cADPR (100 μM; push-pull type of brain microperfusion) elevats OT concentrations in ordinate or subordinate mice[5]. |
性状 | Solid |
Formula | C15H21N5O13P2.xNH3 |
结构分类 |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | -20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |