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Kobusin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Kobusin图片
CAS NO:36150-23-9
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品名称
自旋七叶素
产品介绍
Kobusin 是从Pnonobio biondii Pamp分离的双环氧木脂素。 Kobusin 是CFTR和 CaCCgie 氯化物通道的激活剂,也是ANO1/CaCC (calcium-activated chloride channel)通道的抑制剂。
生物活性

Kobusin is a bisepoxylignan isolated from thePnonobio biondii Pamp. Kobusin is an activator ofCFTRand CaCCgie chloride channels and a inhibitor ofANO1/CaCC (calcium-activated chloride channel) channel[1][2].

体外研究
(In Vitro)

Kobusin could activate the function of CFTR and CaCCgie (CaCC expressed in gastrointestinal epithelial cells) chloride channels. Notably, Kobusin could inhibit the activities ANO1/CaCC chloride channel in ANO1/CaCC-expressing FRT cells[1].

体内研究
(In Vivo)

In charcoal transit study, Kobusin mildly reduced gastrointestinal motility in mice[1].

分子量

370.40

Formula

C21H22O6

CAS 号

36150-23-9

中文名称

自旋七叶素

结构分类
  • Others
来源
  • Plants
  • Magnoliaceae
  • Magnolia biondiiPamp.
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.