CAS NO: | 77337-73-6 |
包装 | 价格(元) |
10 mM * 1 mL in Water | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
生物活性 | Acamprosate calcium(Campral EC) is aGABA receptor agonistand modulator of glutamatergic systems; reduces alcohol consumption in animal models of alcohol addiction. IC50 value: Target:GABA receptorAcamprosate, or N-acetyl homotaurine, is an N-methyl-D-aspartate receptor modulator approved by the Food and Drug Administration (FDA) as a pharmacological treatment for alcohol dependence.Acamprosate has low bioavailability, but also has an excellent tolerability and safety profile. In comparison with naltrexone and disulfiram, which are the other FDA-approved treatments for alcohol dependence, acamprosate is unique in that it is not metabolized by the liver and is also not impacted by alcohol use, so can be administered to patients with hepatitis or liver disease (a common comorbid condition among individuals with alcohol dependence) and to patients who continue drinking alcohol. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 200.24 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C5H10NO4S.1/2Ca | ||||||||||||||||
CAS 号 | 77337-73-6 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: H2O : 100 mg/mL(499.40 mM;Need ultrasonic) DMSO :< 1 mg/mL(insoluble or slightly soluble) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |