Baclofen-d4 is the deuterium labeled Baclofen. Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropicGABA_Breceptor (GABA_BR)agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABA_Breceptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research^[1][2][3].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

217.69

C₁₀H₈D₄ClNO₂

1189938-30-4

巴氯芬 d4

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.