D-Cycloserine is anantibioticwhich targets sequentialbacterialcell wall peptidoglycan biosynthesis enzymes. D-Cycloserine is a partialNMDAagonist that can improve cognitive functions. D-Cycloserine can be used for multidrug-resistant tuberculosis research^[1][2].

D-Cycloserine selectively potentiates the duration of motor cortical excitability enhancements induced by anodal transcranial direct current (tDCS). D-Cycloserine alone does not modulate excitability.^[1].
Chronic D-Cycloserine (40 mg/kg; 5 days/week; for 2 weeks) significantly reduces nicotine self-administration selectively in rats with low baseline nicotine use, but is ineffective with the rats with higher levels of baseline nicotine self-administration^[3].

102.09

Solid

C₃H₆N₂O₂

68-41-7

D-环丝氨酸

• Antibiotics
• Other Antibiotics

Streptomyces

Room temperature in continental US; may vary elsewhere.

H₂O : 25 mg/mL(244.88 mM;Need ultrasonic)

DMSO : 1 mg/mL(9.80 mM;Need warming)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

• 1.

  请依序添加每种溶剂： PBS

  Solubility: 11.11 mg/mL (108.83 mM); Clear solution; Need ultrasonic