CAS NO: | 27876-94-4 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | Transcrocetin (trans-Crocetin), extracted from saffron (Crocus sativus L.), acts as anNMDA receptorantagonist with high affinity[1]. Transcrocetin (trans-Crocetin) is capable of crossing the blood-brain barrier and reach the central nervous system (CNS)[2]. | ||||||||||||||||
IC50& Target |
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体外研究 (In Vitro) | Transcrocetin (trans-Crocetin), a saffron metabolite originating from the crocin apocarotenoids, has been shown to exert strong NMDA receptor affinity and is thought to be responsible for the CNS activity of saffron.To ensure unchanged viability of Caco-2 cells throughout the transport experiments, cellular mitochondrial dehydrogenase activity of Caco-2 cells is measured by MTT assay after a 24 h incubation period with the test compounds: Hydroalcoholic saffron extract saffron extract (SE, 0.5-1 mg/mL) and crocin-1 (250-1000 μM) reveal no negative significant changes in cellular viability. Transcrocetin at 10 μM level does not change viability while higher concentrations (40-160 μM) reduces significantly cellular viability[1]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 328.40 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C20H24O4 | ||||||||||||||||
CAS 号 | 27876-94-4 | ||||||||||||||||
中文名称 | 藏红花酸;西红花酸;番红花酸 | ||||||||||||||||
结构分类 |
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来源 |
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
*该产品在溶液状态不稳定,建议您现用现配,即刻使用。 | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 1 mg/mL(3.05 mM;Need ultrasonic and warming) 配制储备液
* 请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液;该产品在溶液状态不稳定,建议您现用现配,即刻使用。 |