| CAS NO: | 139051-78-8 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 50mg | 电议 |
| 生物活性 | L-689560 is a potentN-methyl-D-aspartate (NMDA)receptor antagonist at the GluN1 glycine binding site. L-689560 is widely used as a radiolabeled ligand in binding studies and used for study the roles of NMDA receptors in normal neurological processes as well as in diseases[1][2]. | ||||||||||||
| 体外研究 (In Vitro) | L-689560 is a 2-carboxytetrahydroquinoline antagonist[2]. | ||||||||||||
| 体内研究 (In Vivo) | L-689560 (1 mg/kg, ip) significantly reduces the neuroprotective effect of glycine after glycine receptors and the channel activity of NMDA receptors (NMDARs) are suppressed. L-689560 blocks glycine-induced increase of Akt phosphorylation in the MCAO model[1]
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| 分子量 | 380.23 | ||||||||||||
| 性状 | Solid | ||||||||||||
| Formula | C17H15Cl2N3O3 | ||||||||||||
| CAS 号 | 139051-78-8 | ||||||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| 储存方式 |
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