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TC HSD 21
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TC HSD 21图片
CAS NO:330203-01-5
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
TC HSD 21 是一种有效的 17β-hydroxysteroid dehydrogenase type 3 (17⛚-HSD3) 抑制剂,IC50 为 14 nM。 TC HSD 21 对 17β-HSD 同工酶和核受体具有出色的选择性。
Cas No.330203-01-5
化学名(Z)-5-(3-bromo-4-hydroxybenzylidene)-3-(4-methoxyphenyl)-2-thioxothiazolidin-4-one
Canonical SMILESCOC1=CC=C(N(C2=S)C(/C(S2)=C([H])/C3=CC(Br)=C(O)C=C3)=O)C=C1
分子式C17H12BrNO3S2
分子量422.32
溶解度<42.23mg/ml in DMSO
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

TC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor with an IC50 of 14 nM. TC HSD 21 shows excellent selectivity over 17β-HSD isoenzymes and nuclear receptors[1].

References:
[1]. Harada K,et al. Identification of oxazolidinediones and thiazolidinediones as potent 17β-hydroxysteroid dehydrogenase type 3 inhibitors. Bioorg Med Chem Lett. 2012 Jan 1;22(1):504-7.