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Zonisamide-d4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Zonisamide-d4图片
CAS NO:1020720-04-0
包装与价格:
包装价格(元)
500 μg电议
5mg电议

产品名称
唑尼沙胺 d4
产品介绍
Zonisamide-d4 (AD 810-d4) 是 Zonisamide 的氘代物。Zonisamide (AD 810) 是锌酶碳酸酐酶 (carbonic anhydrase) 的抑制剂,对人类线粒体同工酶 hCA II 和 hCA V 作用的Ki值分别为 35.2 nM 和 20.6 nM。Zonisamide 具有抗癫痫活性。Zonisamide 可用于癫痫、癫痫发作和帕金森病的研究。
生物活性

Zonisamide-d4 (AD 810-d4) is the deuterium labeled Zonisamide. Zonisamide (AD 810) is an inhibitor of zinc enzymecarbonic anhydrase(CA), withKis of 35.2 nM and 20.6 nM for human mitochondrial isozyme hCA II and hCA V, respectively. Zonisamide has antiepileptic activity. Zonisamide can be used for the rsearch for epilepsy, seizures and Parkinson's disease[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

216.25

Formula

C8H4D4N2O3S

CAS 号

1020720-04-0

中文名称

唑尼沙胺 d4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.